Nephroprotective effects of (−)-α-bisabolol against ischemic-reperfusion acute kidney injury
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چکیده
منابع مشابه
Acute Administration of Estradiol Protects against Spinal Ischemic-Reperfusion Injury in Male Rabbits
Introduction: Postoperative neurological deficit is the most devastating complication after thoracoabdominal aortic aneurysm repair. Despite demonstrated neuroprotective effects of estradiol, its protective efficacy against spinal cord ischemia-reperfusion and underlying mechanisms are not yet elucidated. Methods: Two groups, each of 10 New Zealand white male rabbits, were studied. Control g...
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Although cisplatin is an anticancer drug that has activity against malignant tumor, it often causes nephrotoxicity. Previous reports have confirmed that the saponins from the leaves of P. quinquefolium (PQS) exerted many pharmacological activities. However, the renoprotective effects of PQS were still unknown. The purpose of the present research was to discuss renoprotective effect of PQS in a ...
متن کاملNephroprotective activity of Mammea africana stem bark against paracetamol induced kidney injury
Background & Aim: Mammea africana sabine (Guttiferae) stembark commonly used traditionally to treat various diseases and ailments was evaluated for nephroprotective activity against paracetamol – induced kidney injury in rats to confirm its use in the treatment of kidney diseases. Experimental: The nephroprotective effect of the extract was evaluated by the determination of some kidn...
متن کاملNephroprotective activity of Mammea africana stem bark against paracetamol induced kidney injury
Background & Aim: Mammea africana sabine (Guttiferae) stembark commonly used traditionally to treat various diseases and ailments was evaluated for nephroprotective activity against paracetamol – induced kidney injury in rats to confirm its use in the treatment of kidney diseases. Experimental: The nephroprotective effect of the extract was evaluated by the determination of some kidn...
متن کاملNFAT5 is protective against ischemic acute kidney injury.
NFAT5 is a transcription factor that protects the kidney from hypertonic stress and also is activated by hypoxia. We hypothesized that NFAT5 mitigates the extent of renal damage induced by ischemia-reperfusion injury (IRI). Mice were subjected to IRI by unilateral clamping of the left renal pedicle for 30 minutes followed by reperfusion. After 3 hours of reperfusion, the level of NFAT5 mRNA was...
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ژورنال
عنوان ژورنال: Phytomedicine
سال: 2016
ISSN: 0944-7113
DOI: 10.1016/j.phymed.2016.11.008